Its main areas of activity include: + trade union and human rights + economy, society and the workplace + equality and non-discrimination + international solidarity.
The ITUC adheres to the principles of trade union democracy and independence, as set out in its Constitution. It is governed by four-yearly world congresses, a General Council and an Executive Bureau. The chief executive of the ITUC is its General Secretary Guy Ryder, supported by Deputy General Secretaries Mamounata Cisse and Jaap Wienen.
The process of regional unification to create ITUC regional organizations is taking place, with the Asia-Pacific Regional Organization (ITUC-AP) created on September 2007.
The African regional unification will take place on November 2007 and the Americas on March 2008
The ITUC also cooperates closely with the European Trade Union Confederation, including through the Pan-European Regional Council, which was created on March 2007.
The ITUC has close relations with the Global Union Federations and the Trade Union Advisory Committee to the OECD (TUAC), working together through the Global Unions Council.
The ITUC works closely with the International Labour Organisation. It maintains contacts with several other UN Specialised Agencies.
Along with its Regional Organisations and their sub-offices, the ITUC has offices in Amman, Geneva, Moscow, New York, Sarajevo, Vilnius and Washington DC.